Additive Effects of Iodine and Thiourea in the Treatment of Hyperthyroidism.

Effects of Methimazol and Propyl-thiouracial in the Treat­ment of Hyperthyroidism in Tehran

The response to methimazole and propylthiouracil was evaluated in patients with toxic goiter residing in Tehran, an area of iodine deficiency. Treatment with methimazole, 10 mg twice daily, in 15 patients decreased FT4I from 22.7±6.8 to 12.1±2.5, 10.8±2.8 and 6.0±4.3, 8, 14 and  28 days after treatment respectively. Corresponding FT 3I values were 415±90, 196±36, 162±44 and 117±4 6.At  28 day...

Radioiodine therapy for hyperthyroidism

Radioiodine therapy is the safest, simplest, least expensive and most effective method for treatment of hyperthyroidism. The method employed in this research was a systematic bibliographic review, in which only valid studies or the clinically detailed enough open-labeled studies using validated scales were used. Iodine-131 (I-131) acts by the destructive effect of short-range beta radiation on ...

Evaluation of Radioiodine Therapy in the Refractory Hyperthyroidism

Background: Thyrotoxicosis is a clinical state with potentially multiple etiologies, clinical presentations, and treatments. Thyrotoxicosis is a clinical condition that results from inappropriate function of thyroid hormone in the body tissues. During the early 1950s, radioactive iodine was used as a definitive treatment method. During the last two decades, radioactive iodine has been recognize...

Thiourea and Related Compounds in the Treatment of Hyperthyroidism *

The use of thyroid-depressant agents in the control of hyperthyroidism has raised questions concerning their relationship to other goitrogens and their mode of action. Other problems have been encountered as well, particularly with respect to toxic reactions, the effect of preliminary iodine administraton, and the control of the hypothyroid state which may result. The information available on t...

Minimum Dosage of Thiourea, given Together with Iodine Medication, Necessary for the Production and Maintenance of a Remission in Hyperthyroidism.